Product Details
The Abbott RealTime HBV is an in vitro polymerase chain reaction (PCR) assay for the quantitation of Hepatitis B Virus (HBV) DNA in human plasma or serum from HBV-infected individuals. The Abbott RealTime HBV assay is intended for use in conjunction with clinical presentation and other laboratory markers as an indicator of disease prognosis and for use as an aid in assessing viral response to antiviral treatment as measured by changes in plasma or serum HBV DNA levels.
Abbott RealTime HBV is engineered to quantify all HBV genotypes A-H.
The selection of a highly conserved region within the Surface gene provides for the accurate detection of genotypes A-H. The location of the target region in the N terminal third of the Surface gene ensures that the assay is not impacted by YMDD mutants, HBsAg escape mutants, or drugresistant mutants, as this region is essential for the assembly and secretion of subviral particles, and tolerates only minor structural changes.
Abbott RealTime HBV is engineered to quantify all HBV genotypes A-H.
The selection of a highly conserved region within the Surface gene provides for the accurate detection of genotypes A-H. The location of the target region in the N terminal third of the Surface gene ensures that the assay is not impacted by YMDD mutants, HBsAg escape mutants, or drugresistant mutants, as this region is essential for the assembly and secretion of subviral particles, and tolerates only minor structural changes.