Special stains are methods that usually apply a dye or chemical that has an affinity for the special tissue part that is to be shown. They support the presence/or absence of specific cell types, formations and/or microorganisms to be observed microscopically.
This term defines a large number of alternative staining techniques and histochemical methods that are utilised in circumstances where H&E cannot give all the data required by a pathologist or researcher. The most extensively utilised stain in medical diagnosis. This special stain acts as the basis upon which besides stains may be requested to approve the diagnosis.
Purple defines the Nuclear proteins stain whereas orange/red defines the cytoplasm and other tissue elements stain. These procedures utilise a variety of staining methods to more easily visualise parts of tissue using histology microscopes. In principle, they act by taking the help of intra- and extra-cellular chemical reactions among the tissue components and dyes. They utilise a chemical or dye with an affinity for whatever is under examination, enabling specific tissues, structures, or even microorganisms to be stained.