PharmDx
PharmDx is a term used by several companies that develop and market diagnostic tests and companion diagnostic tools for personalized medicine. These tests are used to identify specific biomarkers, mutations, or other genetic or molecular characteristics that are associated with a particular disease or condition.
The goal of personalized medicine is to use this information to tailor treatments to the unique needs of individual patients. By identifying patients who are most likely to respond to a particular therapy or who are at high risk of adverse reactions, personalized medicine can help to optimize treatment outcomes and minimize the potential for harm.
PharmDx tests can be used in a variety of clinical settings, including cancer treatment, infectious disease diagnosis, and pharmacogenomics (the study of how genetic variation affects drug response). By providing clinicians with more targeted and precise information about a patient's disease or condition, PharmDx tests can help to improve the overall quality of care and outcomes for patients.
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c-kit, otherwise known as CD117 and stem cell factor receptor, is a 145 kDa type III transmembrane receptor tyrosine kinase encoded by the c-Kit proto-oncogene.
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EGFR pharmDx Kit is a qualitative immunohistochemical assay. It includes all reagents necessary to identify the expression of epidermal growth factor receptor (EGFR) protein on the surface of normal and neoplastic cells.The kit will provide reproducible results with its’s standard protocol. EGFR is indicated as an aid in identifying colorectal cancer patients eligible for treatment with Erbitux® (cetuximab) or Vectibix™ (panitumumab).
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ER/PR pharmDx Kit is indicated as an aid in identifying patients eligible for treatment with anti-hormonal or aromatase inhibitor therapies as well as an aid in the prognosis and management of breast cancer.
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HER2 IQFISH pharmDx is the latest Dako HER2 diagnostic kit indicated as an aid in the assessment of patients for whom Herceptin™ treatment is considered.
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HercepTest Kits
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PD-L1 IHC 22C3 pharmDx Advancing Immunotherapy Options Cytotoxic T cells work to detect and eliminate infected cells and tumor cells from the body.
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PD-L1 IHC 28-8 pharmDx Advancing Immunotherapy Options Cytotoxic T cells work to detect and eliminate infected cells and tumor cells from the body.
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TOP2A IQFISH pharmDx is designed to detect amplifications and deletions (copy number changes) of the TOP2A gene using fluorescence in situ hybridization (FISH) technique on formalin-fixed, paraffin-embedded human breast cancer tissue specimens.
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