Cytogenetics
Cytogenetics is the study of chromosomal composition, location and capacity in a cell which involves the examination of chromosome number and appearance, the actual location of genes on chromosomes, and chromosomal conduct in cycles of cell division.
Chromosome irregularities are seen through expansion, deletion rearrangements or adjustment of hereditary material. These irregularities can be a symptom of phenotypic anomalies of the patient or their infection states and chromosome analysis precludes this.
Karyotyping is a visual perception of the chromosomes under a magnifying instrument through chromosome counting and its analysis.
FISH is a molecular strategy that utilizes fluorescent tests that bind to a specific part of the chromosome which is utilized to recognize and localize the presence or non appearance of specific DNA arrangements.
DSS gives a one-stop solution for Cytogenetics with a full scope of products from Sample refined to Sample Analysis with the product from companies like Applied Spectral Imaging, Euroclone and Genial Helix. Our answers range from Interactive to completely mechanized system.
We organise workshops regularly for confidence building and backing measure normalization in labs.
We additionally help in the examination of difficult specimens.
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BMGS (Bone Marrow Growth Supplement) is a ProCell Cytogenetics Reagent that has a marked stimulatory effect on cell growth and morphology in Bone Marrow samples by exposing the cells in culture to a complex mixture of known growth promoters.
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Buffered Hypotonic Solution is a ProCell Cytogenetics Reagent that is a hypotonic solution developed for bone marrow specimens.
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CRA (Chromosome Resolution Additive) is a ProCell Cytogenetics Reagent that prevents chromosome contraction and encourages chromosome elongation by loosening the chemical bonding within the supercoiled structure of the chromosome.
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Cytoclear is a ProCell Cytogenetics Reagent which is an effective, easy-to-use product that improves the quality of both brightfield and FISH samples by removing troublesome cytoplasm.
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ELS (Erythrocyte Lysis Solution) is a ProCell Cytogenetics Reagent that lyses red blood cells, sometimes found in amniotic fluid and bone marrow samples.
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Lymphocyte Growth Supplement is a ProCell Cytogenetics Reagent that is a complex mixture of growth promoters that have a marked stimulatory effect on peripheral lymphocyte cultures.
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MAS (Metaphase Arresting Solution) is a ProCell Cytogenetics Reagent that is a highly refined solution of colchicine/vinblastine sulphate in PBS, used to increase the percentage of metaphase cells for chromosomal studies.
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Optimal Hypotonic Solution is a ProCell Cytogenetics Reagent which is developed for acute leukaemia bone marrow and tumour cells, also useful with problem blood and other problematic sample types.
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Other Cytogenetic Culture Media Products are also available from Euroclone
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Postnatal cytogenetic analysis refers to the karyotyping of samples derived from a variety of tissues: peripheral blood, bone marrow and skin fibroblast.
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Pre-Hypotonic Solution is a ProCell Cytogenetics Reagent that was developed to address this clumping problem. Optimal metaphase swelling can therefore subsequently be achieved by your hypotonic solution.
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Prenatal Analysis Cytogenetic Culture Media Reagents include Chorionic Villi and In Situ
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ASI offers a range of whole chromosome painting probes for human, mouse and rat chromosomes.
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