Fluorescence In Situ Hybridization (FISH)
Fluorescence in situ hybridization (FISH) is a lab technique for distinguishing and finding a particular DNA succession on a chromosome. The strategy depends upon the representing chromosomes to a little DNA sequence considered a test that has a fluorescent molecule attached to it. The fluorescently named DNA finds its matching section on one of the chromosomes, where it sticks. By looking at the chromosomes under a microscope, a scientist can discover the region where the DNA is bound in view of the fluorescent dye appended to it. This information uncovers the area of that piece of DNA in the starting genome. The probe sequence binds to its comparing sequences on the chromosome.
DSS provides a wide range of products for FISH such as Abbott and Dako. Our solutions vary from interactive to a fully automated system. We conduct regular Hands-on Seminars for confidence building and support assay standardization in Labs and also help in the analysis of different cases.
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The UroVysion® Bladder Cancer Kit (UroVysion Kit) is FDA approved and designed to detect aneuploidy for chromosomes 3, 7, 17, and loss of the 9p21 locus via fluorescence in situ hybridization (FISH) in urine specimens from persons with hematuria suspected of having bladder cancer.
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AneuVysion, which utilizes patented fluorescence in situ hybridization (FISH) technology applied to uncultured amniocytes, provides detection of trisomies 13, 18, and 21 (Down syndrome) and sex chromosome aneusomies in as little as 24 hours.
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In situ hybridization (ISH) techniques are used to localize specific nucleic acid sequences within the DNA in cells in tissues or cytological preparations, on chromosomes or in whole mounts.
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In situ hybridization (ISH) techniques are used to localize specific nucleic acid sequences within the DNA in cells in tissues or cytological preparations, on chromosomes or in whole mounts.
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Genetic Probes are used for detection of chromosomal anomalies at prenatal, postnatal and preimplantation stage. These probes enable rapid, sensitive and specific dection, identification & characterization of chromosome anomalies.
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Abbott Molecular offers a wide range of Vysis DNA Fluorescence in situ Hybridization (FISH) products for the effective and rapid identification of genetic aberrations associated with hematopoietic disorders.
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The PathVysion HER-2 DNA Probe Kit II (PathVysion Kit II) is designed to detect amplification of the HER-2/neu gene via fluorescence in situ hybridization (FISH) in formalin-fixed, paraffin-embedded human breast and gastric cancer tissue specimens.
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The detection of genetic aberrations in solid tumors with DNA Fluorescence in situ Hybridization (FISH) probe technology is a powerful means to diagnose and more efficiently treat a wide range of cancers. Vysis offers a comprehensive line of direct labeled DNA probes for solid tumor assessment.
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