Product Details
Somatic Hypermutation test is done for identifying clonal rearrangements of the immunoglobulin heavy chain (IGH) gene. It can help in the following ways:
- Assessing the extent of somatic hypermutation (SHM) in the variable (VH) gene sequence (IGHV) in patients with chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL)
- Evaluating new research and methods in malignancy studies
Some examples of Gel Detection Assays from Invivoscribe are: IGH Somatic Hypermutation Assay v2.0 - Gel Detection, IGH Somatic Hypermutation Assay v2.0 MegaKit - Gel Detection.
- Gel Detection – Agarose TBE Gels (RECOMMENDED)
- Gel Detection – Polyacrylamide TBE Gels
- Gel Detection – Heteroduplex Analysis