DSS: Redefining Biotechnology & Life Science in India

cappilary-cell
3i

Home > Applications & Specialities > Microscopy > 3i Lattice LightSheet

3i Lattice LightSheet

Lattice LightSheet uses ultra-thin sheets of light to image 3D cellular dynamics for hundreds of volumes at dozens of frames per second at diffraction-limited resolution and super-resolution. Invented by Nobel Laureate Dr. Eric Betzig of the Howard Hughes Medical Institute Janelia Research Campus, this microscope has been applied to biological systems spanning four orders of magnitude in space and time. An extremely sensitive primary objective coupled with a custom-designed illumination system allows optical sectioning using extremely low light doses for imaging with unprecedented duration. 3D experiments previously limited by phototoxicity in just seconds or minutes can now be continued safely for hours or days. The combination of high spatiotemporal resolution, speed and sensitivity make the Lattice LightSheet the ultimate tool in a new era for living cell microscopy.

Early successful applications of this instrument include the diffusion of single transcription factors in a spheroid of stem cells, 3D dynamic instability of microtubules during mitosis, formation of the immunological synapse in T cell/antigen presenting cell (APC) interactions, neutrophil motility in a 3D matrix, and embryogenesis in C elegans and Drosophila melanogaster.

About

3i Imaging Instruments in India

3i was established in 1995 by a group of young and dynamic scientists working in the fields of cell biology, immunology, neuroscience, and computer science. At 3i, they aim to provide advanced multidimensional microscopy platforms, with its modular design and user-friendly technology, that meet the evolving needs of the biological research community.

3i (Intelligent Imaging Innovations) designers and manufacturers provide cutting-edge live cell and intravital microscopy imaging platforms that are driven by 64-bit SlideBook software. DSS is a key distribution partner for their representation in India.

More Products

BX51WI

The BX51WI is a high-performance upright microscope meticulously designed for advanced in vivo and…

MLPA Assays for Neuromuscular Disorders

MLPA Assays are useful in finding out those who have Neuromuscular Disorders

Thermobrite

Abbott Molecular ThermoBrite® System offers an easy, safe, system for in-situ hybridization procedures.

CX33

Designed to streamline everyday laboratory routines, the CX33 delivers clear, bright images with minimal…

Testimonials & Reviews

Right Arrow
Left Arrow
Dr. (Prof.), Nitesh Mohan
Dr. (Prof.), Nitesh Mohan
Professor & Head, Department of Pathology, RMCH Bareilly

DSS's expertise, dedication, and professionalism were outstanding in making the Karyotyping & FISH workshop a great success. Their knowledge and valuable insights empowered all the participants with practical skills, receiving highly positive feedback from both students as well as faculty members.

Read More
Dr. Chhaya Chande, Professor & HOD, Microbiology
Dr. Chhaya Chande, Professor & HOD, Microbiology
GGMCJJ Hospitals, Mumbai

“Ms. Megha Dhumal (Assistant Manager- Application) has done a satisfactory demonstration of the running of the Abbott Sample preparation machine model m2000sp and the Abbott RT-PCR machine model m2000rt. We appreciate the effort made by the DSS team under these difficult conditions to help our lab to carry out the imperative Covid-19 tests.”

Read More
Dr Sunil K Arora, Professor, Deptt of Immunopathology
Dr Sunil K Arora, Professor, Deptt of Immunopathology
PGIMER, Chandigarh

“We are using Confocal Microscope and one Fluorescence Microscope. Both are working fine. The after sales services by DSS have been excellent for functioning & upkeep of the microscopes. The applications support by experts from DSS is very useful. Keep it up!”

Read More