Product Details
SALSA® MLPA® Probemixes for Cancer Predisposition are used for determining DNA copy number variations in individuals who have a genetic predisposition to various cancers, including breast, ovarian, colorectal, endometrial, gastric, and small bowel cancer, among others. MLPA Assay is a simple, robust and multiplex PCR-based assay. It is a semi-quantitative assay targetting crucial genes and regions of BRCA1 (P002 BRCA1; P087 BRCA1 confirmation), BRCA2 (P045 BRCA2/CHEK2; P090 BRCA2; P077 BRCA2 confirmation), and Lynch Syndrome (P008 PMS2; P003 MLH1/MSH2; P072 MSH6-MUTYH). With PCR amplicons being fluorescently labelled and quantified using capillary electrophoresis, this technology offers an invaluable tool for both diagnostic and research applications. Pack sizes of 25, 50 and 100 reactions.