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Home > Applications & Specialities > Oncology > MLPA
MLPA
MLPA is a semi-quantitative technique used to detect copy number variation associated with a disease. It was developed as a proprietary technology by MRC Holland for the detection of copy number variations which is considered the gold standard in this field and now being used all over the world to study tumours and hereditary disorders. MLPA (Multiplex Ligation-dependant Probe Amplification (MLPA) is a multiplex PCR based technology that enables the copy number variation (CV) detection of up to 60 DNA sequences in a single reaction. 96 DNA samples can be processed contemporaneously with results being available within 24 hours. Over 350 assays targeting various genetic diseases are available.


BCR ABL Quantitative RT-PCR Kit – Major
IS quantitative, one-step RT-PCR for quantifying the IS ratios of BCR-ABL Major (M-BCR) p210 transcript in CML patient samples.
Applications & Specialities, Cancer Diagnostics Kit, Early cancer detection, Infectious Diseases, MLPA, olympus microscope, Pathology Lab Equipments, Precision Medicine, Real Time PCR, RT-PCR, RT-PCR, NeoDx, Clinical Diagnostics
BCR ABL Quantitative RT-PCR Kit – Major, Minor, Micro
Evaluates the molecular response up to 5 log reduction which is undetectable BCR-ABL1.
Applications & Specialities, Cancer Diagnostics Kit, Early cancer detection, Infectious Diseases, MLPA, olympus microscope, Precision Medicine, Real Time PCR, RT-PCR, RT-PCR, NeoDx, Clinical Diagnostics
BCR ABL Qualitative RT-PCR Kit – Major, Minor, Micro
Single-Tube, Multiplex Real-Time PCR Assay for sensitive and specific detection of Major (M-BCR) p210, Minor (m-BCR) p190, and Micro (μ-BCR) p230 BCR-ABL transcripts.
Applications & Specialities, Infectious Diseases, MLPA, olympus microscope, Precision Medicine, Real Time PCR, RT-PCR, RT-PCR, NeoDx, Clinical Diagnostics
SALSA® digitalMLPA Probemix D006 Multiple Myeloma
The SALSA digitalMLPAProbemix D006-A1 Multiple Myeloma is a research use only (RUO) assay for the detection of deletions, gains or amplifications of genes and chromosomal regions mentioned in Table 2 that are recurrently altered in multiple myeloma, such as 1p, 1q, 13q and 17p, as well as for the detection of BRAF p.V600E point mutation.
Applications & Specialities, Genetic Disorders, MLPA, MLPA, Multiplex Ligation-Dependent Probe Amplification (MLPA), MRC HOLLAND, Clinical Diagnostics
SALSA® digitalMLPA Probemix D007 Acute Lymphoblastic Leukemia
The SALSA digitalMLPA Probemix D007-A1 Acute lymphocytic leukemia is a research-use-only (RUO) assay for the detection of deletions, gains or amplifications in 52 specific target genes and three chromosomal regions (5q, iAMP21 and PAR1), which are related to acute lymphoblastic leukemia (ALL).
Applications & Specialities, Genetic Disorders, MLPA, MLPA, Multiplex Ligation-Dependent Probe Amplification (MLPA), MRC HOLLAND, Clinical Diagnostics
Testimonials & Reviews



Dr. (Prof.), Nitesh Mohan
Professor & Head, Department of Pathology, RMCH Bareilly
DSS's expertise, dedication, and professionalism were outstanding in making the Karyotyping & FISH workshop a great success. Their knowledge and valuable insights empowered all the participants with practical skills, receiving highly positive feedback from both students as well as faculty members.

Dr. Chhaya Chande, Professor & HOD, Microbiology
GGMCJJ Hospitals, Mumbai
“Ms. Megha Dhumal (Assistant Manager- Application) has done a satisfactory demonstration of the running of the Abbott Sample preparation machine model m2000sp and the Abbott RT-PCR machine model m2000rt. We appreciate the effort made by the DSS team under these difficult conditions to help our lab to carry out the imperative Covid-19 tests.”

Dr Sunil K Arora, Professor, Deptt of Immunopathology
PGIMER, Chandigarh
“We are using Confocal Microscope and one Fluorescence Microscope. Both are working fine. The after sales services by DSS have been excellent for functioning & upkeep of the microscopes. The applications support by experts from DSS is very useful. Keep it up!”

Dr Pramod Kumar Bajaj
MD, Spermprocessor Pvt Ltd
“Really excited to see the DSS Pathology solutions exhibition booth at APCON 2019 along with Magnus. We think all the upcoming technology had been displayed along with your efforts to make it Indigenous (Made in India) is highly appreciated. Wish you all the best. Keep it up!”

Dr. Sreejesh S, Associate Professor, Dept of Hematology
PGIMER, Chandigarh
“My experience with DSS so far has been very good till now. We are getting good support in both purchase as well as in troubleshooting. Very good experience with Mr Arun, Mr Manoj, Mr Mahesh and all others from the DSS team.”

Dr Sudha S Murthy, Department of Pathology and Laboratory Medicine
BIACH & RI, Hyderabad
“I am happy with DSS and associated with 19 years and use Dako antibody. Happy with Supply but need improvement.”

Dr S Radhika MD, PhD
Professor, Deptt. Of Cytology & Gynaec Pathology, PGIMER, Chandigarh
“PGI Cytology Dept. has had a long association with DSS- Olympus Microscopy Division. They have provided excellent services- after sales service. The product is also of very good quality. We have had no problems with their products and services are of very good quality.”

Dr Nuzhat Husain
RMLIMS, Lucknow
“Have been using Dako Reagents and Dako antibodies for a while. Services and products have been good and timely.”

Dr Minu Singh
Assistant Professor, PGIMER, Chandigarh
“MRC Holland MLPA products provided by DSS are of good quality, have never faced any quality issues with their product or shipping condition. They provide prompt response upon any query.”

Mr. Krishnani Professor, SGPGI, Lucknow
“My experience with DSS so far has been excellent for the last 30 years- sales and service experience. Microscope products are very useful and sturdy with high precision.”
