Fluorescence In Situ Hybridization (FISH)
Fluorescence in situ hybridization (FISH) is a molecular cytogenetic technique which uses a fluorescent probe that binds to those segments which are complementary to the gene of interest. FISH is generally an Interphase study but can be done on Metaphase as well as on cultured cells; a study on the genetic level which further helps in diagnosis of addition, deletion and most probably cryptic Abnormalities.
- Delivers results faster as compared to other Cytogenetics Studies.
- An important tool for understanding variety of Haematological malignancies( AML, ALL, CML, CLL), Solid tumors( Her2, ALK, ROS) and Various Genetic Abnormalities (Down’s Syndrome, DiGeorge Syndrome, Prader-Willi Syndrome, Angelman Syndrome).
DSS provides a wide range of products for FISH such as Abbott, Olympus and ASI. Our solutions range from interactive to a fully automated system. We conduct regular Hands-on Workshops for confidence building and support assay standardization in Labs and also help in the analysis of different cases.
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AneuVysion, which utilizes patented fluorescence in situ hybridization (FISH) technology applied to uncultured amniocytes, provides detection of trisomies 13, 18, and 21 (Down syndrome) and sex chromosome aneusomies in as little as 24 hours.
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In situ hybridization (ISH) techniques are used to localize specific nucleic acid sequences within the DNA in cells in tissues or cytological preparations, on chromosomes or in whole mounts.
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In situ hybridization (ISH) techniques are used to localize specific nucleic acid sequences within the DNA in cells in tissues or cytological preparations, on chromosomes or in whole mounts.
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Genetic Probes are used for detection of chromosomal anomalies at prenatal, postnatal and preimplantation stage. These probes enable rapid, sensitive and specific dection, identification & characterization of chromosome anomalies.
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Abbott Molecular offers a wide range of Vysis DNA Fluorescence in situ Hybridization (FISH) products for the effective and rapid identification of genetic aberrations associated with hematopoietic disorders.
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HER2 IQFISH pharmDx is the latest Dako HER2 diagnostic kit indicated as an aid in the assessment of patients for whom Herceptin™ treatment is considered.
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HyperChrome is the perfect Instrument for denaturation & hybridization procedures during FISH experiments.
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The PathVysion HER-2 DNA Probe Kit II (PathVysion Kit II) is designed to detect amplification of the HER-2/neu gene via fluorescence in situ hybridization (FISH) in formalin-fixed, paraffin-embedded human breast and gastric cancer tissue specimens.
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The detection of genetic aberrations in solid tumors with DNA Fluorescence in situ Hybridization (FISH) probe technology is a powerful means to diagnose and more efficiently treat a wide range of cancers. Vysis offers a comprehensive line of direct labeled DNA probes for solid tumor assessment.
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Abbott Molecular ThermoBrite® System offers an easy, safe, system for in-situ hybridization procedures.
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TOP2A IQFISH pharmDx is designed to detect amplifications and deletions (copy number changes) of the TOP2A gene using fluorescence in situ hybridization (FISH) technique on formalin-fixed, paraffin-embedded human breast cancer tissue specimens.
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The UroVysion® Bladder Cancer Kit (UroVysion Kit) is FDA approved and designed to detect aneuploidy for chromosomes 3, 7, 17, and loss of the 9p21 locus via fluorescence in situ hybridization (FISH) in urine specimens from persons with hematuria suspected of having bladder cancer.
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VP2000 is a consolidated workstation for automated front-end FISH* processing
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