In situ hybridization (ISH) techniques are used to localize specific nucleic acid sequences within the DNA in cells in tissues or cytological preparations, on chromosomes or in whole mounts. We provide a wide variety of probes and kits aimed at the most predominant molecular tests performed in anatomic pathology. The IQFISH hybridization buffer is non-toxic and allows genomic DNA probe hybridization to be performed outside a fume hood in just 60-120 minutes. The short hybridization time results in a turnaround time of about 4 hours for a complete FISH staining from deparaffinization to mounting. Hybridizer is a hands-free denaturation and hybridization instrument designed for semi-automated, slide-based fluorescence and chromogenic in situ hybridization (FISH and CISH, respectively) on histology and cytology samples.
FISH probes use two differently labeled DNA-probes a Texas Red-labeled DNA probe giving red fluorescent signals and fluorescein-labeled PNA probes giving green fluorescent signals.
Following FISH Probes are available
- IQFISH Panel for Lung Cancer
- Split Signal FISH DNA Probes
- SureFISH ALK/RET/ROS1 Probes