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HER2 IQFISH pharmDx

HER2 IQFISH pharmDx
HER2 IQFISH pharmDx is the latest Dako HER2 diagnostic kit indicated as an aid in the assessment of patients for whom Herceptin™ treatment is considered.
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Product Details

Our pharmDx Solution is a portfolio of all-in-one pharmDx kits that lead to optimal diagnostic results within companion diagnostics. Correct results the first time help select the right therapy for each patient - every time. pharmDx is all about personalized medicine pharmDx kits make a difference to the assessment of patient treatment. The validated kits have the right specificity and sensitivity. Correct results the first time lead to fewer reruns and will help select the right therapy for each patient - every time. We help improve patient care by delivering fast results with great confidence and reducing time from biopsy to diagnosis.

The human HER2 gene with the generic name ERBB2 (also known as NEU) encodes the HER2 protein or p185HER2. The HER2 protein is a membrane receptor tyrosine kinase with homology to the epidermal growth factor receptor (EGFR). The HER2 gene is a normal component present in two copies in all normal diploid cells. In a fraction of patients (15-20%) with breast cancer, the HER2 gene is amplified as a part of the process of malignant transformation and tumor progression. HER2 gene amplification leads to overexpression of the HER2 protein on the surface of breast cancer cells. HER2 gene amplification and receptor prevalence correlates with poor breast cancer prognosis, including relapse-free and overall survival. HER2 IQFISH pharmDx is the latest Dako HER2 diagnostic kit indicated as an aid in the assessment of patients for whom Herceptin™ treatment is considered.
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