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Home > Applications & Specialities > Genetic Disorders > Cytogenetic Solutions > ProCell Cytogenetics Reagents > Cytoclear Cytoplasm Remover
Cytoclear Cytoplasm Remover
ProCell Cytogenetics Reagents product range was developed in collaboration with scientists working in a clinical oncology cytogenetics unit. The ProCell range is designed to improve culture failure rates, mitotic index, metaphase spreading, banding resolution and overall quality of bone marrow, lymphoma, solid tumour, blood, CVS and Amniocentesis samples for cytogenetic analysis.
Cytoclear is a newly developed product (consisting of a mixture of protein detergents) which can quickly dissolve and remove persistent cytoplasm (mainly caused by inadequate hypotonic treatment) during the methanol:acetic acid fixation stage of the chromosome harvesting procedure. In particular, it dissolves the lipid and glycoprotein structure of which cytoplasm is mainly composed. Clumped metaphases that would normally be impossible to analyse, can now be restored. Cytoclear is a useful tool in FISH hybridizations as it enables the probe to reach the target by removing barrier cytoplasm.
Cytoclear is an effective, easy-to-use product that improves the quality of both brightfield and FISH samples by removing troublesome cytoplasm. Cytoclear is incorporated into the fix stage of the harvest, usually requiring little change to existing procedures and is appropriate for both freshly fixed and archived fixed suspensions. Cytoclear can be used to
rescue cultures that have harvested badly.
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Testimonials & Reviews
Dr. (Prof.), Nitesh Mohan
Professor & Head, Department of Pathology, RMCH Bareilly
DSS's expertise, dedication, and professionalism were outstanding in making the Karyotyping & FISH workshop a great success. Their knowledge and valuable insights empowered all the participants with practical skills, receiving highly positive feedback from both students as well as faculty members.
Dr. Chhaya Chande, Professor & HOD, Microbiology
GGMCJJ Hospitals, Mumbai
“Ms. Megha Dhumal (Assistant Manager- Application) has done a satisfactory demonstration of the running of the Abbott Sample preparation machine model m2000sp and the Abbott RT-PCR machine model m2000rt. We appreciate the effort made by the DSS team under these difficult conditions to help our lab to carry out the imperative Covid-19 tests.”
Dr Sunil K Arora, Professor, Deptt of Immunopathology
PGIMER, Chandigarh
“We are using Confocal Microscope and one Fluorescence Microscope. Both are working fine. The after sales services by DSS have been excellent for functioning & upkeep of the microscopes. The applications support by experts from DSS is very useful. Keep it up!”
Dr Pramod Kumar Bajaj
MD, Spermprocessor Pvt Ltd
“Really excited to see the DSS Pathology solutions exhibition booth at APCON 2019 along with Magnus. We think all the upcoming technology had been displayed along with your efforts to make it Indigenous (Made in India) is highly appreciated. Wish you all the best. Keep it up!”
Dr. Sreejesh S, Associate Professor, Dept of Hematology
PGIMER, Chandigarh
“My experience with DSS so far has been very good till now. We are getting good support in both purchase as well as in troubleshooting. Very good experience with Mr Arun, Mr Manoj, Mr Mahesh and all others from the DSS team.”
Dr Sudha S Murthy, Department of Pathology and Laboratory Medicine
BIACH & RI, Hyderabad
“I am happy with DSS and associated with 19 years and use Dako antibody. Happy with Supply but need improvement.”
Dr S Radhika MD, PhD
Professor, Deptt. Of Cytology & Gynaec Pathology, PGIMER, Chandigarh
“PGI Cytology Dept. has had a long association with DSS- Olympus Microscopy Division. They have provided excellent services- after sales service. The product is also of very good quality. We have had no problems with their products and services are of very good quality.”
Dr Nuzhat Husain
RMLIMS, Lucknow
“Have been using Dako Reagents and Dako antibodies for a while. Services and products have been good and timely.”
Dr Minu Singh
Assistant Professor, PGIMER, Chandigarh
“MRC Holland MLPA products provided by DSS are of good quality, have never faced any quality issues with their product or shipping condition. They provide prompt response upon any query.”
Mr. Krishnani Professor, SGPGI, Lucknow
“My experience with DSS so far has been excellent for the last 30 years- sales and service experience. Microscope products are very useful and sturdy with high precision.”