Cytogenetics

Cytogenetics

Cytogenetics is the study of chromosomal structure, location and function in cell which includes the study of chromosome number and appearance, the physical location of genes on chromosomes, and chromosomal behaviour in processes of cell division.

 

- Chromosome abnormalities are seen through addition, deletion or rearrangement of genetic material.

- These abnormalities can be indications for phenotypic abnormalities of the patient or their disease states and chromosome analysis rules this out .

- Karyotyping is visual observation of the chromosomes under the microscope through chromosome counting and its analysis.

- FISH is a molecular technique that uses fluorescent probes that bind to specific parts of the chromosome which is used to detect and localize the presence or absence of specific DNA sequences

DSS provides a one stop solution for Cytogenetics with a full range of products from Sample culturing to Sample Analysis with products like Euroclone, ADS Biotech, Abbott, Olympus and ASI. Our solutions range from Interactive to fully automated systems.

We conduct regular workshops for confidence building and support assay standardization in labs.

We also help in analysis of difficult samples.

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  1. ABBOTT MOLECULAR AneuVysion in India

    AneuVysion, which utilizes patented fluorescence in situ hybridization (FISH) technology applied to uncultured amniocytes, provides detection of trisomies 13, 18, and 21 (Down syndrome) and sex chromosome aneusomies in as little as 24 hours.

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  2. GENIAL GENETICS Anticlotting Reagent in India

    ACR (AntiClotting Reagent) is a ProCell Cytogenetics Reagent used to reduce culture failure rates, thereby reducing the requirement for repeat sampling in both blood and bone marrow samples.

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  3. EUROCLONE AutoChrome in India

    Autochrome is a robotic dispenser for automated processing of chromosome preparations from adherent cells cultures, in particular amniocytes and chorionic villi samples.

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  4. APPLIED SPECTRAL IMAGING Bandview in India

    GenASIs Bandview is a software module for karyotyping diagnostics, offering cytogenetic labs with accurate, repeatable and standardized analysis.

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  5. GENIAL GENETICS Bone Marrow Growth Supplement in India

    BMGS (Bone Marrow Growth Supplement) is a ProCell Cytogenetics Reagent that has a marked stimulatory effect on cell growth and morphology in Bone Marrow samples by exposing the cells in culture to a complex mixture of known growth promoters.

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  6. GENIAL GENETICS Buffered Hypotonic Solution in India

    Buffered Hypotonic Solution is a ProCell Cytogenetics Reagent that is a hypotonic solution developed for bone marrow specimens.

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  7. OLYMPUS BX53 in India

    The BX53 is a versatile system microscope that can be configured to meet virtually any research need.

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  8. GENIAL GENETICS Chromosome Resolution Additive in India

    CRA (Chromosome Resolution Additive) is a ProCell Cytogenetics Reagent that prevents chromosome contraction and encourages chromosome elongation by loosening the chemical bonding within the supercoiled structure of the chromosome.

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  9. EUROCLONE Cooling Unit for OptiChrome Plus in India

    Cooling Unit for OptiChrome Plus is a cooler designed for cooling water, intended for use in combination with OptiChrome PLUS.

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  10. GENIAL GENETICS Cytoclear Cytoplasm Remover in India

    Cytoclear is a ProCell Cytogenetics Reagent which is an effective, easy-to-use product that improves the quality of both brightfield and FISH samples by removing troublesome cytoplasm.

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  11. GENIAL GENETICS Erythrocyte Lysis Solution in India

    ELS (Erythrocyte Lysis Solution) is a ProCell Cytogenetics Reagent that lyses red blood cells, sometimes found in amniotic fluid and bone marrow samples.

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  12. APPLIED SPECTRAL IMAGING FISHview (Liquid FISH) in India

    It is a multicolor/multidimensional image capture and enhancement software.

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  13. ABBOTT MOLECULAR Genetic Probes in India

    Genetic Probes are used for detection of chromosomal anomalies at prenatal, postnatal and preimplantation stage. These probes enable rapid, sensitive and specific dection, identification & characterization of chromosome anomalies.

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  14. ADS Biotec HANABI PI Metaphase Chromosome Harvester in India

    The HANABI-PI is specifically created for small to mid-size throughput, enables processing of up to 16 suspension cultures per run and eliminates variability compared to manual processing methods.

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  15. ADS Biotec HANABI PII Plus Metaphase Chromosome Harvester in India

    The HANABI-PII Plus reduces hands-on time of the entire harvesting process by 75% allowing time for other specialized tasks, providing increased throughput for your laboratory. Capable of processing up to 24 samples per run eliminates variability compared to manual processing methods.

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  16. ADS Biotec HANABI PIII Plus Metaphase Chromosome Harvester in India

    The HANABI-PIII Plus reduces hands-on time of the entire harvesting process by 75% allowing time for other specialized tasks, providing increased throughput for your laboratory.

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  17. ADS Biotec HANABI PIV Metaphase Spreader in India

    The HANABI PIV Metaphase Spreader is an automated instrument that provides optimized environmental conditions for the preparation of metaphase chromosome spreads.

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  18. ADS Biotec HANABI PV Metaphase Spreader Mini  in India

    The HANABI PV Metaphase Spreader Mini is an automated instrument designed especially for small to mid-size labs - processing up to 10 samples or 20 slides per run.

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  19. ADS Biotec HANABI PVI Metaphase Spreader Mini  in India

    The HANABI PVI Metaphase Spreader offers the best control to spread cell suspensions to make the chromosome metaphase specimen slides used to analyze chromosomes using FISH, CGH, and G-banding.

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  20. ADS Biotec HANABI-P1000 In-situ Harvester in India

    The HANABI P-1000 is custom designed to radically improve the speed, efficiency and repetitive quality of cytogenetic in situ culture harvesting.

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  21. ADS Biotec HANABI-S1020 Auto Chromosome Staining System in India

    The HANABI-S1020 is designed to radically improve the speed, efficiency and repetitive quality of cytogenetic stained slide specimens. The HANABI-S1020 is capable of processing slides in batches of 20 and features a continuous loading mode allowing the operator to load another batch of slides as the first batch is being processed

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  22. APPLIED SPECTRAL IMAGING Hyperspectral Karyotyping in India

    GenASIs HiSKY performs Hyperspectral Karyotyping analysis, leveraging the benefits of multiplexed spectral imaging to obtain a karyotype which uniquely colors each chromosome and provides a level of detailed analysis not available with any other karyotyping technique.

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  23. GENIAL GENETICS Lymohocyte Growth Supplement in India in India

    Lymphocyte Growth Supplement is a ProCell Cytogenetics Reagent that is a complex mixture of growth promoters that have a marked stimulatory effect on peripheral lymphocyte cultures.

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  24. GENIAL GENETICS Metaphase Arresting Solution in India

    MAS (Metaphase Arresting Solution) is a ProCell Cytogenetics Reagent that is a highly refined solution of colchicine/vinblastine sulphate in PBS, used to increase the percentage of metaphase cells for chromosomal studies.

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