Clonality Based Testing (Gel Detection)

Clonality based testing is done for the identification of clonal B-cell populations highly suggestive of B-cell malignancies. It can help in the following ways:

• Lineage determination of leukemias and lymphomas


• Monitoring and evaluation of disease recurrence


• Detection and assessment of residual disease


• Evaluation of new research and methods in malignancy studies

Some examples of Gel Detection Assays from Invivoscribe are: T Cell Receptor Gamma Chain Gene Rearrangement Assays, TRG Gene Clonality Assay, TCRB Gene Clonality Assay

• Gel Detection – Agarose TBE Gels (RECOMMENDED)


• Gel Detection – Polyacrylamide TBE Gels


• Gel Detection – Heteroduplex Analysis