3i VIVO

Features & Benefits

• The imaging of blood clot formation and the recruitment and involvement of blood coagulation proteins was first captured in real time in multiple channels on a VIVO system. The 3D reconstruction over time of the forming blood clot was captured with multiple fluorescent probes using VIVO, both wide field deconvolution and Spinning Disk Confocal.
• VIVO used with Laser Ablation, Ferric Chloride, Rose Bengal Injuries.
• VIVO with particle tracking has been used to capture and count white cell rolling along a vascular tree.
• VIVO is assisting in the formation of new targeted therapies for Hemophilia and other blood related genetic diseases.
• The identification of cancer tumor markers and their roles in physiological processes have been recorded using VIVO.
• Blood vessel sprouting can be recorded over time and computed with VIVO(tm) and Slidebook software.
• Enzymologic parameters using fluorescent FRET substrates introduced into tissues of living animals are imaged with VIVO.
• Calcium transients in circulating cells have been measured using VIVO.
• Intracellular Signal Transduction phenotyping in vivo
• Pharmaceutical Therapeutic Targeting and Screening in live animals