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EntroGen’s GIST mutation screening panel is a real-time polymerase chain reaction (PCR)-based assay that uses allele-specific primers to identify the presence of somatic mutations in c-KIT and PDGFRA genes.
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EntroGen’s One-Step Detection kits provide reagents to detect and quantify the fusion gene transcripts listed below using total RNA isolated from blood or bone marrow.
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All kits require a real-time PCR instrument capable of detecting FAM and VIC fluorescent probes. Additionally, the Cell-Free EGFR Mutation Detection kit requires the capability to detect ROX and CY5 fluorescent probes. All reagents required for PCR amplification/detection, as well as validated reaction controls, are included. Columns and reagents for DNA or RNA isolation are not included.
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Entrogen's kits are polymerase chain reaction (PCR)-based assays that use allele-specific primers in a multiplex reaction to identify the presence of BRAF, NRAS, and c-Kit mutations. The assays work by amplifying mutant-specific sequences in samples that contain a mixture of mutant and wild-type DNA and rely on fluorescent probes for detection. Each reaction contains primer sets and probes for detection of the mutations, as well as an endogenous control gene.
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EntroGen’s Sample Quality Assessment kits provide reagents, positive controls, and standards (if applicable) to detect and quantify the amplifiable DNA extracted from patient samples or adaptor-indexed libraries intended for downstream qPCR and NGS assays, respectively.
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Thyroid Cancer Mutation Panel provides reagents for detection of point mutations in BRAF and RAS genes, as well as RET/PTC1, 3 and PAX8/PPARγ fusion genes variants.
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Epidermal growth factor receptor (EGFR) is a membrane protein that plays a central role in sending signals that promote cell growth and proliferation. Its tyrosine kinase (TK) domain triggers several downstream effectors that lead to the activation of the Ras-Raf-MAPK track. Overexpression and oncogenic mutations that constitutively activate the TK domain of EGFR have been found in various solid tumours. Additionally, excessive activation of EGFR is associated with advanced stages of cancer and a poor prognosis.
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ER/PR pharmDx Kit is indicated as an aid in identifying patients eligible for treatment with anti-hormonal or aromatase inhibitor therapies as well as an aid in the prognosis and management of breast cancer.
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ELS (Erythrocyte Lysis Solution) is a ProCell Cytogenetics Reagent that lyses red blood cells, sometimes found in amniotic fluid and bone marrow samples.
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The high quality of Milestone frozen sections can only be obtained by freezing the specimens with PrestoCHILL and by processing the slides with FineFIX (patent n. EP 1 455 174 B1) before staining.
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In situ hybridization (ISH) techniques are used to localize specific nucleic acid sequences within the DNA in cells in tissues or cytological preparations, on chromosomes or in whole mounts.
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Small enought to fit any grossing station or ventilated hood, the FixSTATION 1RH is a game changer in controlling the fixation process.
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The FlashFREEZE unit is used to standardize the flash freezing processing step of biospecimens.
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SAFEHOOD is the new Bioair fume cupboard with activated carbon filters for the removal of a variety of toxic fumes, gases or vapours from the exhausted air.
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Genetic Probes are used for detection of chromosomal anomalies at prenatal, postnatal and preimplantation stage. These probes enable rapid, sensitive and specific dection, identification & characterization of chromosome anomalies.
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Genial Pedigree Draw Revolutionary pedigree drawing software with the emphasis on quick and correctly laid out pedigree diagrams.
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Milestone is striving to improve the laboratory work environment by developing safer and greener reagents and accessories.
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"Hanabi Avatar™, the optimized growth media designed for the establishment and propagation of organoids. ADS Biotec proudly offers this advanced growth media for the cultivation of organoids from various tissues, including: HANABI Avatar™ Oviduct Organoid Growth Media - Human/Murine, HANABI Avatar™ Colon Organoid Growth Media – Human/Murine, HANABI Avatar™ Liver Organoid Growth Media – Murine. With Hanabi Avatar™, you can be assured of superior performance and reliability in organoid culture. HANABI Avatar medias are for use with both normal and tumor tissues and offer significantly improved performance over competitive culture media."
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The HANABI-PI is specifically created for small to mid-size throughput, enables processing of up to 16 suspension cultures per run and eliminates variability compared to manual processing methods.
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The HANABI-PII Plus reduces hands-on time of the entire harvesting process by 75% allowing time for other specialized tasks, providing increased throughput for your laboratory. Capable of processing up to 24 samples per run eliminates variability compared to manual processing methods.
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The HANABI-PIII Plus reduces hands-on time of the entire harvesting process by 75% allowing time for other specialized tasks, providing increased throughput for your laboratory.
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The HANABI PIV Metaphase Spreader is an automated instrument that provides optimized environmental conditions for the preparation of metaphase chromosome spreads.
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The HANABI PV Metaphase Spreader Mini is an automated instrument designed especially for small to mid-size labs - processing up to 10 samples or 20 slides per run.
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The HANABI PVI Metaphase Spreader offers the best control to spread cell suspensions to make the chromosome metaphase specimen slides used to analyze chromosomes using FISH, CGH, and G-banding.
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Clinical Diagnostics
The Clinical Diagnostics Division (erstwhile Life Sciences Division) was conceptualized in 2003 as a life science research and diagnostics solutions arm for DSS Imagetech Pvt. Ltd. Today with Abbott Molecular & Dako (Agilent Pathology Solutions) at its forefront, the Clinical Diagnostics Division primarily focusses on clinical diagnostics and is among the leaders in the Molecular Diagnostics market in India.
The Division provides solutions for cancer diagnosis and pre & post-natal genetic aberration diagnosis as well as diagnosis of infectious diseases like HIV, HBV, HCV, CMV, CT/NG, Sepsis, etc.
Through its various principals, DSS covers technologies such as FISH, IHC, RealTime PCR based Viral Load Testing, Integrated Chromosome Profiling (ICP), MLPA, DNA Flow Technology, karyotyping, culture media etc.
This division aims to achieve high growth in the coming years by taking advantage of its prime position in the molecular testing market in India by introducing more tests for diseases which are relevant to the Indian conditions.
